ME Kit
Our Vn96 synthetic peptide technology is available as a research kit through our partner, New England Peptide

The METM Kit for Extracellular Vesicle Isolation

  • Specific and rapid isolation of extracellular vesicles (exosomes and microvesicles) in as little as 45 minutes
  • No ultracentrifugation
  • Works for multiple sample types. (Plasma, Urine, Cell culture media, etc.)
  • Can be modified to fit your specific needs. (Multiple chemistries, added to beads, etc.)
  • Comes complete with positive and negative control

How the METM Kit works

The Vn96 peptide reagent (US Patent # 8,956,878, EU Patent # 2688904) is designed to bind specifically to canonical Heat Shock Proteins (HSPs) on EVs. Our product binds to EVs in minutes, forming a precipitate easily isolated using a standard benchtop centrifuge. Once collected, the EVs can be used in multiple assay types.
ME Protocol

Possible downstream applications using the ME Kit:

  • Nanoparticle tracking analysis (NTA)
  • Nucleic acid isolation: DNA, RNA, miRNA
  • Next Generation Sequencing
  • Proteomics
  • Structural studies (EM or AFM)
  • Metabolomics
  • Fluorescent labeling of EVs
  • Cellular uptake and microscopy
  • EV-mediated cellular tranformation assay
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